Search results for "PLA membrane"

showing 2 items of 2 documents

Plasma modified PLA electrospun membranes for actinorhodin production intensification in Streptomyces coelicolor immobilized-cell cultivations

2017

Most of industrially relevant bioproducts are produced by submerged cultivations of actinomycetes. The immobilization of these Gram-positive filamentous bacteria on suitable porous supports may prevent mycelial cell-cell aggregation and pellet formation which usually negatively affect actinomycete submerged cultivations, thus, resulting in an improved biosynthetic capability. In this work, electrospun polylactic acid (PLA) membranes, subjected or not to O2-plasma treatment (PLA-plasma), were used as support for immobilized-cell submerged cultivations of Streptomyces coelicolor M145. This strain produces different bioactive compounds, including the blue-pigmented actinorhodin (ACT) and red-p…

0301 basic medicinePolyestersSegmented filamentous bacteriaS. coelicolor immobilizationAnthraquinonesStreptomyces coelicolor02 engineering and technologySecondary metaboliteSettore BIO/19 - Microbiologia GeneraleActinorhodinMicrobiology03 medical and health scienceschemistry.chemical_compoundColloid and Surface Chemistrystomatognathic systemPolylactic acidmedicinePlasma treatmentPhysical and Theoretical ChemistryIncubationMyceliumbiologyElectrospinningPhotoelectron SpectroscopyProdigiosinStreptomyces coelicolorActinorhodin productiontechnology industry and agricultureSettore ING-IND/34 - Bioingegneria IndustrialePLA membraneSurfaces and InterfacesGeneral Medicine021001 nanoscience & nanotechnologybiology.organism_classificationAnti-Bacterial Agents030104 developmental biologyMembraneSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialichemistryBiochemistryMicroscopy Electron Scanning0210 nano-technologyBiotechnologymedicine.drug
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Enhancement of antibiotic productions by plasma modified PLA electrospun membranes in Streptomyces coelicolor immobilized-cell cultivations

2017

This study, encouraging the use of PLA membranes for actinomycetes cultivations, could unveil functional insights associated with antibiotic production and S. coelicolor cellimmobilization

Actinorhodin and Undecylprodigiosin productionRaman spectroscopyPlasma treatmentS. coelicolor immobilization2D-DIGEPLA membraneSettore BIO/19 - Microbiologia Generale
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